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Nutritional Supplement

Vitex

Side Effects

Side effects may include minor stomach upset and a mild skin rash with itching. Vitex is not recommended for use during pregnancy and should not be used concurrently with hormone therapy (e.g., estrogen, progesterone).

References

1. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 108.

2. Sliutz G, Speiser P, Schultz AM, et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 1993;25:253-5.

3. Böhnert KJ. The use of Vitex agnus castus for hyperprolactinemia. Quart Rev Nat Med 1997;Spring:19-21.

4. Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomized, placebo controlled study. BMJ 2001;20:134-7.

5. Lauritzen C, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine 1997;4:183-9.

6. Dittmar FW, Böhnert KJ, Peeters M, et al. Premenstrual syndrome: Treatment with a phytopharmaceutical. Therapiwoche Gynäkol 1992;5:60-8.

7. Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Women Health Gender-Based Med 2000;9:315-20.

8. Halaška M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing Vitex agnus extract: results of a placebo-controlled double-blind study. The Breast 1999;8:175-81.

9. Bone K. Vitex agnus-castus: Scientific studies and clinical applications. Eur J Herbal Med 1994;1:12-5.

10. Milewicz A, Gejdel E, Sworen H, et al. Vitex agnus castus extract for the treatment of menstrual irregularities due to latent hyperprolactinemia. Arzneim Forsch 1993;43:752-6 [in German].

11. Amann W. Improvement of acne vulgaris following therapy with Agnus castus (Agnolyt). Ther Ggw 1967;106:124-6 [in German].

12. Milewicz A, Gejdel E, Sworen H, et al. Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study. Arzneimittelforschung 1993;43:752-6 [in German].

13. Dittmar FW, Böhnert KJ, Peeters M, et al. Premenstrual syndrome: Treatment with a phytopharmaceutical. Therapiwoche Gynäkol 1992;5:60-8.

14. Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Women Health Gender-Based Med 2000;9:315-20.

15. Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomized, placebo controlled study. BMJ 2001;20:134-7.

16. Ma L, Lin S, Chen R, et al. Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Aust N Z J Obstet Gynaecol 2010;50:189-93.

17. Lauritzen C, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine 1997;4:183-9.

18. Dittmar F. Das pramenstruelle Spannungssyndrome. Jiatros Gynakologie 1989;5:4-7.

19. Halaška M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing Vitex agnus extract: results of a placebo-controlled double-blind study. The Breast 1999;8:175-81.

20. Böhnert KJ. The use of Vitex agnus castus for hyperprolactinemia. Quart Rev Nat Med 1997;Spring:19-21.

21. Propping D, Katzorke T. Treatment of corpus luteum insufficiency. Zeitschr Allgemeinmedizin 1987;63:932-3.

22. Gerhard I, Patek A, Monga B, et al. Mastodynon® for female infertility. Randomized, placebo-controlled, clinical double-blind study. Forsch Komplementärmed 1998;5:272-8.

23. Loch E, Böhnert KJ, Peeters M, et al. The treatment of menstrual disorders with Vitex agnus-castus tincture. Der Frauenarzt 1991;32:867-70 [in German].

24. Batchelder HJ, Hudson T, Lewin A, et al. Therapeutic approaches to endometriosis. The Protocol Journal of Botanical Medicine 1996;Spring:25-60.

25. Hudson T. Women's Encyclopedia of Natural Medicine. Los Angeles: Keats Publishing, 1999:79-88.

26. Sliutz G, Speiser P, Schultz AM, et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 1993;25:253-5.

27. Lauritzen C, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine 1997;4:183-9.

28. Bone K. Vitex agnus-castus: Scientific studies and clinical applications. Eur J Herbal Med 1994;1:12-5.

29. Bingel AS, Farnsworth NR. Higher plants as potential sources of galactagogues. Econ Med Plant Res 1994;6:1-54 [review].

30. Mohr H. [Clinical investigations of means to increase lactation.] Dtsch Med Wschr 1954;79:1513-6 [in German].

31. Veal L. Complementary therapy and infertility: an Icelandic perspective. Complement Ther Nurs Midwifery 1998;4:3-6 [review].

32. Sliutz G, Speiser P, Schultz AM, et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 1993;25:253-5.

33. Milewicz A, Gejdel E, Sworen H, et al. Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study. Arzneimittelforschung 1993;43:752-6 [in German].

34. Brown DJ. Herbal Prescriptions for Health and Healing. Roseville, CA: Prima Health, 2000, 235-8.

35. Loch EG, Katzorke T. Diagnosis and treatment of dyshormonal menstrual periods in general practice. Gynäkol Praxis 1990;14:489-95.

36. Milewicz A, Gejdel E, Sworen H, et al. Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study. Arzneimittelforschung 1993;43:752-6 [in German].

37. Dittmar FW, Böhnert KJ, Peeters M, et al. Premenstrual syndrome: Treatment with a phytopharmaceutical. Therapiwoche Gynäkol 1992;5:60-8.

38. Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Women Health Gender-Based Med 2000;9:315-20.

39. Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomized, placebo controlled study. BMJ 2001;20:134-7.

40. Ma L, Lin S, Chen R, et al. Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Aust N Z J Obstet Gynaecol 2010;50:189-93.

41. Lauritzen C, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine 1997;4:183-9.

42. Dittmar F. Das pramenstruelle Spannungssyndrome. Jiatros Gynakologie 1989;5:4-7.

43. Loch E, Böhnert KJ, Peeters M, et al. The treatment of menstrual disorders with Vitex agnus-castus tincture. Der Frauenarzt 1991;32:867-70 [in German].

44. Batchelder HJ, Hudson T, Lewin A, et al. Therapeutic approaches to endometriosis. The Protocol Journal of Botanical Medicine 1996;Spring:25-60.

45. Hudson T. Women's Encyclopedia of Natural Medicine. Los Angeles: Keats Publishing, 1999:79-88.

46. Sliutz G, Speiser P, Schultz AM, et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 1993;25:253-5.

47. Lauritzen C, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine 1997;4:183-9.

48. Bone K. Vitex agnus-castus: Scientific studies and clinical applications. Eur J Herbal Med 1994;1:12-5.

49. Veal L. Complementary therapy and infertility: an Icelandic perspective. Complement Ther Nurs Midwifery 1998;4:3-6 [review].

50. Sliutz G, Speiser P, Schultz AM, et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 1993;25:253-5.

51. Milewicz A, Gejdel E, Sworen H, et al. Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study. Arzneimittelforschung 1993;43:752-6 [in German].

52. Brown DJ. Herbal Prescriptions for Health and Healing. Roseville, CA: Prima Health, 2000, 235-8.

53. Loch EG, Katzorke T. Diagnosis and treatment of dyshormonal menstrual periods in general practice. Gynäkol Praxis 1990;14:489-95.

54. Bingel AS, Farnsworth NR. Higher plants as potential sources of galactagogues. Econ Med Plant Res 1994;6:1-54 [review].

55. Mohr H. [Clinical investigations of means to increase lactation.] Dtsch Med Wschr 1954;79:1513-6 [in German].

56. Amann W. Improvement of acne vulgaris following therapy with Agnus castus (Agnolyt). Ther Ggw 1967;106:124-6 [in German].

57. Amann W. Acne vulgaris and Agnus castus (Agnolyt ™).Z Allgemeinmed 1975;51:1645-58 [in German].

58. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 108.

Copyright © 2020 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2020.

Copyright © 2020 TraceGains, Inc. All rights reserved.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2020.